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EBOLA
(c) 2014 by John W. Apsley, II, MD(E), ND, DC   www.DrApsley.com
 
 
October 12th Report

 


Then listen to my October 22nd Report on the Power Hour with Joyce Riley in the third hour here.
 
December 2014 - Ebola cases escalating. See full CDC report starting on page 1199 here.
 
 
Ebola was discovered in 1976 and has become a part of regular cycles of contagion and death in remote west Africa. There have been 16 cycles of Ebola epidemics since 1976. It is thought to infiltrate into human populations and set off the next round of epidemic by way of hunting, preparing and eating "bush meat" (i.e., transmission to humans occurs from reservoirs of the virus in select groups of animals, such as primates and game, such as fruit bats). Food spit out by infected fruit bats and/or through eating bat meat are thought to be a key part of the Ebola transmission chain. Kids playing in the dung of certain animals or carcasses of animals may also start Ebola outbreaks. After humans are infected, handling dead or dying family members greatly escalates Ebola cases.
 
Ebola virus is a very complex microbe in that it has five different forms (strains), it relentlessly mutates, and four of these strains are lethal to humans. The other one is not fatal and is actually found as a 'regular bug' (is an indigenous virus) within the United States and the Philippines. The most deadly form is unfortunately commonly found in Africa, generally west Africa.
 
More specifically, Ebola is classically spread by encountering bodily fluids from infected patients. Sweat and saliva are not presently considered bodily fluids that will readily transmit the virus to another. But potentially, an infected patient coughing or sneezing could eject contaminated moisture droplets that infect someone standing within a few feet of the infected patient. Remember, despite what some infectious disease specialists have led us to believe, saliva from mouth glands verses mucus lining the sinus and lung passageways are entirely different bodily fluids. More specifically, Ebola loves to attack immune cells, and immune cells are abundant within protective mucus secretions, especially during active infection.
 
Even if protective gear is being worn, carefully removing the protective gear has still resulted in infection. Thus, becoming infected with Ebola is indeed possible without direct, physical contact. Please bear in mind that whenever a person sneezes, the air expelled from the nostrils can attain speeds of up to 100 miles per hour, making it likely to expel tiny or unnoticeable moister droplets outwardly. For this reason, nearly all infected patients here in the U.S. will often be given facial masks to cover their mouth and nasal passageways. However, by far the most common form of transmission is by unprotected touching or making direct physical contact with an infected patient. Since a person, on average, touches their face reflexively up to 10,000 times daily, hand contact with bodily fluids from an infected person can easily make contact with an uninfected person's eyes, nose or mouth. Thus, it is very important to cough or sneeze properly into the crease of a long-sleeved elbow or handkerchief, and wash one's hands routinely as we enter into the Flu & Cold season. 
 
Ebola outbreaks normally 'self-extinguish' if left to its own ends. In other words, the human population that becomes exposed will simply all die-off in short order thereby ending the local plague. This is true only so long as exposed folks are not able to transport themselves far away from the localized outbreak. This observation alone tells us that implementing smart travel bans upon western African nationals is a must during a major Ebola outbreak. With the recent physician who flew out of western Africa after treating Ebola into New York City testing positive for Ebola (October 23, 2014), common sense should rule the day to motivate our government health protection agencies to institute such a tight travel ban. Airport thermal screening alone cannot prevent Ebola cluster outbreaks here in America.
 
The March 2014 Ebola outbreak in west Africa is proving to be an exception to the 15 smaller, self-limiting cycles seen before. As of October 2014, West Africa is currently experiencing roughly 1,000 new cases of Ebola per week. It continues to spread and at present, the CDC expects new Ebola cases in west Africa to dramatically escalate before this cycle is over. For example, it is expected that by the early part of next year, 1.4 million west Africans will be infected, from 10,000 new cases occurring each week  (up from our current level of just 1,000 new cases per week). Of these 1.4 million expected cases by January or February 2015, about 70% are expected to die, or just under 1 million deaths or more per month. Currently, the numbers of those infected are doubling once every 20 to 30 days on average. Therefore, without containment or effective commercial treatment, it becomes easier to see how Ebola could take millions and millions of lives in Africa during this 16th cycle of the disease.
 
Officials warn that unless we institute successful containment procedures by mid-December, 2014 in west Africa, we will not be able to reverse the course of this Ebola epidemic. So far, only complete travel bans have eradicated new sources of infection into Nigeria and Senegal, now declared to be Ebola-free nations. As of this writing, over 30 nations have instituted complete travel bans barring anyone traveling out of the three west African nations of Liberia, Sierra Leone and Guinea. In fact,  two nations (Nigeria and Senegal) were able to free themselves from all cases of Ebola by implementing such smart travel bans. Travel bans work!
 
This Ebola virus incubates unnoticed from 1 to 42 days before flu-like symptoms appear (typically fever, fatigue, nausea, abdominal pains, and muscle and joint pain). Rapid progression then brings on severe symptoms, especially catastrophic dehydration from relentless vomiting and diarrhea. Prior reports that this strain's incubation period is restricted to 1 to 21 days only relate to 95% of those infected. There is an additional 3% of those infected who show longer incubation periods of up to 40 days or longer (see Figure 3, especially Figure 3E of the just referenced NEJM article). Longer incubation periods are known to occur in 'reservoirs' of the virus infected patient (i.e., in reproductive bodily fluids of infected males and breast milk of females for up to 40 days or longer).
 
What makes one strain, the west African 'Zaire ebolavirus' (ZEBOV), so fearsome are three things:
(1) ZEBOV approaches a 90% death rate.
(2) ZEBOV is said to have no cure and basically kills by overproduction of inflammatory chemicals which induce severe hemorrhaging, internal clotting, catastrophic dehydration and organ failure. This perfect storm of inflammatory chemicals may be easily controllable by all-natural safe agents (listed in #6 below).
(3) It only takes from 1 to 10 ZEBOV viruses (called virions) to infect a person. By simply placing a hand down on a counter-top on which an infected person just sneezed, one scratch of the eyelid with a finger can immediately infect a new person. This scenario, or a close approximation of same appears to be the case with the several physicians and nurses specializing in Ebola care and treatment who contracted the disease themselves.
 
As of October, 2014, over 230 health care professionals, including physicians and nurses, have contracted Ebola while provide care to those afflicted in western Africa. Their death rate approaches 70%. Controlling or defeating ZEBOV with latest vaccine methodologies is highly problematic for multiple reasons. For just one example, since ZEBOV easily mutates, it is likely that any single vaccine strategy will only enjoy a limited effective treatment window.1 Even if expensive multiple series of vaccines were to become available and accepted by affected west African populations (many tribes do not trust western medicine), viral mutation (genome neighbors) and emerging reservoirs of isolated animals harboring the virus could render any initially effective vaccine ineffective.
 
These limitations of an effective window for conventional treatments is akin to what we see occur in other seasonal flu bugs. More specifically, flu vaccines are typically from 77% to less than 1% effective because they can only be made from previous flu bugs. A newly mutated bug cannot be made into a vaccine in advance, since it has not arisen yet. In other words, all vaccines are made from prior bugs captured 'after-the-fact' for the vaccine-making process. Because Ebola mutates as does the common flu, viral treatments (vaccine antigens or 'target precise antibodies') will suffer from being obsolete before they can be made in sufficient quantities to treat large numbers of patients infected with newly emerged mutated viruses. It would be much, much better to boost immune function ahead of time naturally, thus putting any new, emerging, mutated viral infection at a disadvantage.
 
Remember the old saying, "An ounce of prevention is worth a pound of cure"?
 
For the record, the science involving the mechanism as to exactly how these select natural treatment methods work suggest they may highly reliable and cost-effective as well as safe. On the other hand, conventional treatments may not be consistently reliable or cost-effective. For one example, natural therapies that boost immune function by dramatically raising interferon levels are not only safe and cost effective but sustainable as well. Before I provide more details on such natural therapies, let's look at what limited success stories there have been to date with conventional treatments. In this manner, it will be crystal clear as to why and how natural anti-viral agents and natural immune-building agents can out-sustain conventional therapies in the long run.
 
CONVENTIONAL TREATMENTS:
1. Isolation and quarantine of those infected while implementing medical-grade sanitation methods.
2. Hydration and electrolyte infusions to keep the patient alive long enough to potentially ramp up their own internal immune response.
3. Direct attachment to the virus with special novel antibodies that jam-up the virus's ability to enter into our body cells. These select antibodies also make it a highlighted target for our immune system to seek and destroy. These special, supply-limited antibodies require direct injection into the blood stream.
4. Vaccines are problematic for many reasons:
a. Necessity to trigger a sufficient immune enhancement related to #5 next
b, Ebola readily mutates, rendering vaccines less effective
c. Single verses multiple dose requirements dramatically alter drug accessibility (expense, patient compliance, etc...).
5. Immune-stimulating drugs (i.e., targeted interferon) to turbo-charge our own immune response to seek and destroy the virus. This kind of interferon is attached to a common non-lethal virus to enhance targeting of the Ebola in the blood stream, and is typically administered by injection. Sublingual and nasal entry forms are under investigation.
 
In summary, these emerging conventional measures are:
(A) Expensive,
(B) Currently extremely limited in terms of commercial availability, and
(C) Prone to losing their effectiveness:
(i) as and when the Ebola virus mutates again and again or
(ii) as and when novel viral reservoirs in select animal species infect humans.
It is clear that conventional treatment success hinges on reactivating the patient's natural immune system to overcome ZEBOV. Therefore, this will also be the key when focusing on all-natural treatment regimens.
 
NATURAL TREATMENTS:
1. Isolation and quarantine of those infected while implementing medical-grade sanitation methods.
2. Hydration techniques such as using all-natural electrolyte solutions commonly available to athletes.
3. Direct attachment onto the virus (while in the blood stream) of oligodynamic nano-silver particles (from the Greek: ŏl'ĭ-gō - meaning small, and dī-nām'ĭk - meaning of great power) and lactoferrin. Oligodynamic nano-silver particles easily cleave and jam-up all viruses studied to date without causing any harm to host tissues. In fact, there are advantages possessed by oligodynamic nano-silver that by all accounts surpass any other known viral treatment regimen because it is not known to lose effectiveness after viruses mutate. Oligodynamic silver works by way of super oxidizing (cleaving) viral surface structures and vital internal viral molecules. Viral mutations are not known to select for resistance to super oxidation assaults by silver when properly administered. So long as the Oligodynamic silver can reach the virus while in the blood stream, and in sufficient quantities, viruses have shown little to no defense against this unique metal. Similarly, lactoferrin has been shown to 'jam-up' viruses, thereby destroying their ability to penetrate and infect human cells. Also, lactoferrin has been shown to directly stimulate the human immune response to viral infections discussed next.
4. Immune-stimulating mushrooms and nutrients such as lactoferrin and zinc turbo-charge our own immune response to seek and destroy the virus. These tools ramp up the immune system's vital levels of internal interferon-gamma by 10-fold or more.
5. Liposomal Vitamin C, with Alpha lipoic acid, Bioflavonoids, Melatonin and Vitamins A, D3 and K2 will ramp up cellular resilience and resistance against all viruses studied to date. Although Ebola has not yet had formal studies with the above, its attributes, structure, shape and size provide no evidence it possesses the means to shield itself from the cleaving effects and immune building effects of the above.
6. The key to buy critical time for the immune system to cure and render the patient immune to ZEBOV is to lessen the effects of the cytokine storm (inflammatory surge). By doing so, this gives the body time to ramp up immune cells to attack and destroy the virus. This requires specialty knowledge involving the causal tier to viral inflammatory cascades:
(a) reducing levels of xanthine oxidase (XO) by herbal medicines;
(b) stamping out the highly inflammatory NF kappa beta molecule (NF-κβ) by simple vitamins or herbal medicines, and
(c) by inhibit production of nitric oxide (NO) by simple amino acids or herbal medicines.
Therefore, precise, specific (1) herbal medicines, (2) vitamins, (3) oligodynamic nano-silver and (4) amino acids can quench and neutralize the main killing power of Ebola cost-effectively and sustainably... 
 
PEAKING IMMUNITY WITH ALL-NATURAL AGENTS
Oligodynamic nano-silver white paper.
 
 
Noni juice and licorice will reduce XO,
 
Vitamins C & E and the medicinal herbs turmeric and green tea will stamp out the key inflammatory cytokine NF-κβ and protect human cell membranes, and
 
The amino acids methionine and NAC will inhibit NO excesses.
 
Selenium and zinc help peak immunity
 
 
Additional References:
________________________ 
 
1. Ebola In America, On: Fox News Live - On The Record with Greta Van Sustern, Interview with Prof. Erica Olmann Saphire of the Scripts Research Institute, October 9th, 2012, 7PM.